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frlO [2017-8-11 16:0:3]
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frlO [2017-8-11 16:0:3]

aminosugar ABC transporter (binding protein)
Locus
BSU32600
Isoelectric point
5.67
Molecular weight
47.86 kDa
Protein length
422 aa Sequence Blast
Gene length
1266 bp Sequence Blast
Function
uptake of sugar amines
Product
aminosugar ABC transporter (binding protein)
Essential
no
Synonyms
yurO
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → ABC transporters → Importers → Uptake of carbon sources
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of amino sugars
  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of amino sugars
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    3,349,761 → 3,351,029

    The protein

    Protein family

  • bacterial solute-binding protein 1 family (according to Swiss-Prot)

    • Localization

  • membrane associated (via FrlM-FrlN) PubMed

    • Expression and Regulation

    Operons

    Genes
    frlB-frlO-frlN-frlM-frlD-yurJ
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • CodY: repression, PubMed, PubMed, in CodY regulon
  • FrlR: repression, PubMed, in FrlR regulon
  • YlxR: regulation, PubMed, in YlxR regulon

    • Regulation

  • FrlB: repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • induced in the absence of YlxR PubMed

    • Additional information

  • the frlB-frlO-frlN-frlM-frlD-yurJ operon is strongly downregulated in a cshA mutant PubMed
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    Biological materials

    Mutant

  • MGNA-A561 (yurO::erm), available at the NBRP B. subtilis, Japan

    • References

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